The perforant path (PP) axonal terminals of entorhinal layer 2 spiny stellate cells delineate the outer molecular layer in DG and lacunosum-moleculare in CA3. B: The layers of the dentate gyrus (DG) and hippocampal area CA3 are defined by the somatic locations and axonal terminals of principal neurons. ) and of an OML cell (dendrites in black, axons in green NMO_00178 from Ref. A: Morphological reconstructions (from NeuroMorpho.Org ) of a rat dentate gyrus semilunar granule cell (dendrites in blue, axons in red NMO_10035 from Ref. In this example, neuron types are divided along the vertical axis based on parvalbumin (PV) expression (one of many molecular biomarkers), along the depth axis based on firing threshold potential (V thresh one of many electrophysiological variables), and along the horizontal axis as to whether they can receive perforant path (PP) input (one of many morphological factors).Īxonal-dendritic patterns and anatomical regions: two sides of the same coin. D: The GABAergic interneurons of hippocampal area CA1 can be grouped on the basis of selected properties across three dimensions in a highly simplified binary classification scheme. The advantages and disadvantages of every technique are color-coded along themes that recur across dimensions: invasiveness, cost, scalability, training time, coverage scope, and resolution. Each approach is suitable to investigate a subset of general properties and specific features based on different techniques. The three main experimental approaches to characterize neuron types. At the same time, this core classification scheme is suitable for aggregating biochemical, physiological, and synaptic information.Īxons circuits classification dendrites neurons. Furthermore, among the features commonly employed to describe neurons, morphology is considerably robust to experimental conditions. Just as the positions of the elements in the periodic table indicate their potential to combine into molecules, axonal and dendritic distributions provide the blueprint for network connectivity. We propose that the patterns of presence or absence of axons and dendrites within known anatomical parcels may serve as the key principle to define neuron types. The situation is not dissimilar to the state of Chemistry prior to Mendeleev's tabulation of the elements. "They're glued to their phones, trying to get whatever information through social media that they could," she said.No one knows yet how to organize, in a simple yet predictive form, the knowledge concerning the anatomical, biophysical, and molecular properties of neurons that are accumulating in thousands of publications every year. Orchestra teacher Kathy Thompson said some students were in tears and eager for updates about their classmates. She also praised "the quick and calm actions of the Woodson leadership and staff" in conducting a safe evacuation. "I know this incident has affected the Woodson community and, as a district, we will provide as much support and assistance for students, staff members, and families as is needed." "FCPS is truly like a family, and as such, we are all deeply concerned about what happened today," Garza said in the release. Students were dismissed at 12:55 p.m., their scheduled time. Parents were notified of the situation, Torre said.įCPS Superintendent Karen Garza said in a release Friday that she was "deeply saddened" by the injuries. Other students were taken to tennis courts.įriday was the last day of the marking period, so students had been scheduled for early dismissal even before the fire occurred, said John Torre, a spokesman for Fairfax County Public Schools. "Anything to take precautionary measures is, I think, the recommended route when it comes to the safety of children and students," Schmidt said.Ĭhopper4 footage showed evacuated students gathering near the football field outside the school. The school was evacuated after the fire, which was contained to a single room. "Firefighters, along with the sprinkler system, put out the fire." "It was a small fire," said Dan Schmidt, from the Fairfax County fire department, said. Two students are experiencing life threatening injuries. One teacher and five students are injured after a classroom fire.
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